POTENT ANTI-TUMOR EFFECT GENERATED BY A NOVEL HUMAN PAPILLOMAVIRUS (HPV) ANTAGONIST PEPTIDE REACTIVATING THE PRB/E2F PATHWAY.

Potent anti-tumor effect generated by a novel human papillomavirus (HPV) antagonist peptide reactivating the pRb/E2F pathway.

Human papillomavirus type 16 (HPV16) E7 is a viral oncoprotein believed to play a major role in cervical cancer.In this study, an antagonist peptide against HPV16E7 protein was first identified from screening the c7c phage display peptide library.The binding specificity and affinity of the selected peptide to Reclining Loveseat HPV16E7 were tested

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Typhoon and flooding occurrences on Chongming Island, Changjiang Estuary, as revealed by a newly acquired sedimentary record

Typhoon-induced storms surges and river flooding events represent two types of natural disasters that affect a wide range, occurring with high frequency and causing serious societal losses.Due to the limited duration of instrumental records, there is an inadequate understanding of the patterns and mechanisms underlying the variations in typhoons an

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Diagnostic capabilities of the virtual bronchoscopy at advanced neoplastic process of esophagus with formation of tracheobronchial fistula: Description of a case

The relevance of the problem is related to the continued increase in the neoplastic processes, and at the same time also to the development and improvement of the endoscopic and CT equipment, and Hayward Commercial Automation Parts thus expanding the diagnostic capabilities.Purpose: The presented research examines the results of the study of a rare

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